FOR PROFESSIONALS

CLINICAL RESEARCH

Clinical Research

InterX is committed to providing the most up to date research to support the application of InterX Therapy as well as demonstrating the clinical efficacy of the technology in randomized, controlled, trials. Many years of research and experience has gone into the development of the InterX device and the training resources available to customers. Please click on the available links to obtain more details of some of the research available. NOTE: Although we can provide copies of and links to the abstracts of articles, copyright prevents us from displaying the full article and/or providing it as a download. For the full published articles, please visit the appropriate journal direct or in the case of an InterX published trial, please contact us to enquire about reprints.

PUBLISHED TRIALS

Read about all our published trials.

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Presented Posters

Read about all our presented posters with their respective presenters and titles

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Case Studies

Click below to read our two case studies

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Supporting Articles

Read about all our numerous articles that support the application of InterX Therapy

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PUBLISHED TRIALS – ABSTRACTS

PRESENTED POSTERS

AUTHOR/PUBLICATION

Presented by Dr. James Dillard at the International Association of the Study of Pain (IASP)
Glasgow, August 2008 – 1419, PF 360

Presented as a poster at the 13th World Congress on Pain, Montreal. Aug 29th – Sept. 2nd, 2010. PM 341

CASE STUDIES

SUMMARY

CPRS, Types I and II

SUPPORTING ARTICLES

Electrode Placement

Ronald Melzack
Prolonged Relief of Pain by Brief, Intense Transcutaneous Somatic Stimulation
Pain, 1 (1975) 357-373

MERYL R. GERSH, STEVEN L. WOLF, VADDADl R. RAO, Evaluation of Transcutaneous Electrical Nerve Stimulation for Pain Relief in Peripheral Neuropathy, A Clinical Documentation
Physical Therapy: Sept 1979

David L Somers, F Richard Clemente
Transcutaneous Electrical Nerve Stimulation for the Management of Neuropathic Pain: The Effects of Frequency and Electrode Position on Prevention of Allodynia in a Rat Model of Complex Regional Pain Syndrome Type II
Physical Therapy . Volume 86 . Number 5 . May 2006

Skin Impedance and Electrode Placement

Sarah P. Shultz, MEd, Jeffrey B. Driban, MEd, Charles B. Swanik, PhD
The Evaluation of Electrodermal Properties in the Identification of Myofascial Trigger Points Arch Phys Med Rehabil Vol 88, June 2007

I. G. Gorodetskyi,et al
Non-invasive interactive Neurostimulation in the post-operative recovery of patients with a trochanteric fracture of the femur
A RANDOMISED, CONTROLLED TRIAL
J Bone Joint Surg [Br] 2007;89-B:1488-94.

Agatha P. Colbert1, Jinkook Yun1, Adrian Larsen2, Tracy Edinger1, William L. Gregory1 and Tran Thong1,3
Skin Impedance Measurements for Acupuncture Research: Development of a Continuous Recording System
1Helfgott Research Institute, National College of Natural Medicine, Portland, OR, 2Miridia Technology Inc.

Skin Impedance and Skin Friction

Raja K Sivamani, Jack Goodman, Norm Gitis, Howard Maibach
Co-efficient of Friction: tribological studies in man- an overview
Skin Research and Technology2003; 9; 227-234

Mechanisms: Pain Relief

Kathleen A. Sluka, PhD PT.
The Basic Science Mechanisms of TENS and Clinical Implications, American Pain Society Bulletin � Volume 11, Number 2, March/April 2001

Lee KH; Chung JM; Willis WD Jr.
Inhibition of primate spinothalamic tract cells by TENS, Journal of Neurosurgery. 62(2):276-87, 1985 Feb

Josimari M. DeSantana, PhD, Valter J. Santana-Filho, MSc, Kathleen A. Sluka, PhD
Modulation Between High- and Low-Frequency Transcutaneous Electric Nerve Stimulation Delays the Development of Analgesic Tolerance in Arthritic Rats
Archives of Physical Medicine and Rehabilitation Volume 89, Issue 4, April 2008, Pages 754-760

Ji-Sheng Han
Acupuncture: neuropeptide release produced by electrical stimulation of different frequencies, Neuroscience Research Institute, Peking University,
TRENDS in Neurosciences Vol.26 No.1 January 2003

Higher Intensity: Increased Analgesia

Ronald Melzack
Prolonged Relief of Pain by Brief, Intense Transcutaneous Somatic Stimulation, Pain, 1 (1975) 357-373

Garrison, D.W., and Foreman, R.D.
Effects of Prolonged Transcutaneous Electrical Nerve Stimulation (TENS) and Variation of Stimulation Variables on Dorsal Horn Cell Activity in Cats. European Journal of Physical Medicine and Rehabilitation, 17(1997)87-94

Sjolund, B.H. (1985)
Peripheral nerve stimulation suppression of C-fiber evoked flexion reflex in rats. Part 1: Parameters of continuous stimulation. Journal of Neurosurgery, 63, 612-616

Sjolund, B.H. (1988)
Peripheral nerve stimulation suppression of C-fiber evoked flexion reflex in rats. Part 2. Parameters of low rat train stimulation of skin and muscle afferent nerves. Journal of Neurosurgery, 68, 279-283

Mechanism: Anti-inflammatory Effect

HYUN-WOO KIM, et al
The Anti-Inflammatory Effects of Low- and High-Frequency Electroacupuncture Are Mediated by Peripheral Opioids in a Mouse Air Pouch Inflammation Model
THE JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
Volume 12, Number 1, 2006, pp. 39-44

Varying Frequencies: Increased Analgesia

Ji-Sheng Han.
Acupuncture: neuropeptide release produced by electrical stimulation of different frequencies, Neuroscience Research Institute, Peking University,
TRENDS in Neurosciences Vol.26 No.1 January 2003

David L Somers, F Richard Clemente.
Transcutaneous Electrical Nerve Stimulation for the Management of Neuropathic Pain: The Effects of Frequency and Electrode Position on Prevention of Allodynia in a Rat Model of Complex Regional Pain Syndrome Type II
Physical Therapy . Volume 86 . Number 5 . May 2006

Stimulation Frequencies: Analgesic Tolerance

Josimari M. DeSantana, PhD, Valter J. Santana-Filho, MSc, Kathleen A. Sluka, PhD
Modulation Between High- and Low-Frequency Transcutaneous Electric Nerve Stimulation Delays the Development of Analgesic Tolerance in Arthritic Rats Archives of Physical Medicine and Rehabilitation Volume 89, Issue 4, April 2008, Pages 754-760